Preparation and properties of a liver esterase which hydrolyzes S-acetoacetyldithioloctanoic acid and related thioesters.
نویسندگان
چکیده
The occurrence of thioesterases hydrolyzing thioesters of monothiol coenzymes, e.g. glutathione (l-3) and wenzyme A (P6), is well documented. In the course of experiments on the metabolism of acetoacetyl thioesters (7), it was found that liver enzyme fractions catalyzed the hydrolysis of (f)-S-acetoacetyl6 ,E&dithioloctanoic(dihydrolipoic) acid (Reaction 1) and ( &S-acetyld, Sdithioloctanoic(dihydrolipoic) acid (Reaction 2).
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 236 شماره
صفحات -
تاریخ انتشار 1961